I have seen this issue for a long time and I am a little annoyed when I add new remote connections and want to have them inherit login information from the parent connection and found out that the inheritance icon is greyed out. To resolve this I have to Save my connections first ,close and reopen Mremote. Can this be resolved.
When you start your computer from sleep mode ,the icons Inheritance,Default Properties,Default Inheritance from Config section are greyed if Mremote was running when the computer was in sleep mode. I attached the screen shot for your reference
WIndows 7, Windows 10